Arpan Satsangi

San Antonio, TX
Age 18

Optimization of Biomimetic Osteoblast Response
on Phospholipid Modified Implant Surface for Bone Regeneration

Optimization of Biomimetic Osteoblast Response on Phospholipid Modified Implant Surface for Bone Regeneration

Research of metallic bone implants lead to the development of a novel product-based biomedical technology which has evolved new surface modified metallic implants having a potential of better host tissue attachment and integration, brought about by a biomemetic or natural mechanism of induction of the process of bone regeneration and modeling on the modified surface. This project attempts to coat implant materials with a natural, bone growth-accelerating substance to make it more compatible to host tissue. This modification makes the implant appear natural to the adjacent host tissue. The conundrum of modifying titanium implants, such that bone cells are stimulated and natural bone-crystallites are formed has been solved, and the structure of active molecular species has been optimized by this systematic research.