Natl Gallery Banner
 
pillar  

Preya Shah

Combating Cancer: Design and Synthesis of
Dual Warhead Tumor-Targeting Drug Conjugate

Setauket, NY
Grade: 12

Shah

Combating Cancer: Design and Synthesis of Dual Warhead Tumor-Targeting Drug Conjugate

This simple, but highly effective "dual-warhead" approach is a novel concept of combining two cytotoxic agents at a molecular level. It allows the drug to fight cancer cells with multiple modes of attack. In addition, this invention targets cancer cells using biotin, a vitamin, as a tumor-targeting molecule. Biotin has not been previously utilized for this purpose. Preya's invention addresses the problems of existing chemotherapeutic agents which are suboptimal due to side effects and the development of drug resistance. The tumor-targeting molecule in her invention guides the warheads selectively into cancer cells. Since each warhead has a different mechanism of action, the conjugate can attack cancer cells on two fronts. This invention provides an innovative approach for the simultaneous delivery of multiple cytotoxic agents to cancer cells, enhancing effectiveness in destroying cancer cells without harming healthy cells.

 

   
NMOE
The National Gallery for America's Young Inventors is a program of NMOE.org
 

Edison Innovation Foundation

Proudly sponsored by
The Edison Innovation
Foundation

 


Please support our efforts by using this link for your online purchases:

Amazon.com

 
Questions or Comments? Want to learn more? Please email us at info@nmoe.org

Visitors Welcomed to Date =
 

 We gratefully acknowledge the generous support of the Christopher Columbus Fellowship Foundation for the National Gallery of America's Young Inventors, 1999-2006

Christopher Columbus Fellowship Foundation

 
   

The National Gallery for America's Young Inventors ™ is the only nationally recognized hall of fame for student inventors, established in 1993 and given permission by the adult National Inventors Hall of Fame Board in Washington, D.C. to archive and enshrine great student inventions and inventors K-12.


The National Gallery for America's Young Inventors ™ is owned and administered by The National Museum of Education
©1988-2017 National Museum of Education... In Partnership for America's Future, Inc. - All Rights Reserved

No portion of this site (including text, photos, drawings, renderings, sounds, etc.) may be used in any form without
express written consent of The National Museum of Education, Inc. • All violators will be prosecuted.
National Museum of Education, Inc. •1145 Highbrook Street, Suite 308 • Akron, Ohio 44301 • 330-376-8300

• www.nmoe.org • Funding provided by the support of businesses, granting agencies, and individual contributors.