Chloe Sow

Escaping Synthetic Carcinogens: An integration of chemically based testing methods in a comprehensive, multi-use origami microfluidic paper-based analytical device (μPAD) for detecting carcinogens and other harmful substances in personal care and cosmetic

Chloe Sow

 

Grade: 12

Kirkland, Washington

Inducted: 2023

 

3D-origami microfluidic paper-based analytical devices (μPADs) with the capability to colorimetrically detect carcinogens and other harmful substances present in liquid-based personal care products.  Conceptually, the 3D paper microfluidic channels facilitate fluid wicking through capillary action, allowing for the transport and mixing of reagents for colorimetric detection, as the unique design enables for fluid propagation between layers without the need for bonding agents, resulting in a cost-effective and straightforward fabrication process. 

Constructed with chromatography paper, wax, and customizable colorimetric reagents, this device offers an inexpensive, rapid, and accessible tool for the general population to identify unknown irritants and toxins in their personal care products.  In our proof-of-concept method, we successfully prototyped accessible (portable, low-cost, and easy-to-fabricate)3D origami μPADs, achieving multi-use (useable for >1 samples) and multi-detection (testing for >1 harmful substances) capacities.